Effect of dietary and lifestyle interventions in pregnancy* on secondary fetal and neonatal outcomes (ranked as critically important by Delphi survey, except for infant hyperbilirubinaemia). Summary estimates are relative risks unless stated otherwise
| No of studies | No of participants | Relative risk (95% CI) | P value | I2 (%) | |
|---|---|---|---|---|---|
| Dietary intervention | |||||
| Intrauterine death | 228 30 | 1320 | 0.15 (0.02 to 1.20) | 0.07 | 0 |
| Admission to neonatal intensive care unit | 228 31 | 1962 | 0.98 (0.66 to 1.47) | 0.93 | 77 |
| Shoulder dystocia | 328 31 34 | 2082 | 0.38 (0.21 to 0.69) | 0.001 | 0 |
| Birth trauma | 228 31 | 1961 | 0.36 (0.11 to 1.23) | 0.10 | 0 |
| Respiratory distress syndrome | 228 31 | 1962 | 1.05 (0.48 to 2.28) | 0.91 | 58 |
| Infant hypoglycaemia | 328 31 34 | 1877 | 1.05 (0.83 to 1.33) | 0.69 | 41 |
| Infant hyperbilirubinaemia | 228 31 | 1898 | 0.84 (0.64 to 1.10) | 0.19 | 0 |
| Mixed approach | |||||
| Intrauterine death | 0 | — | — | — | — |
| Admission to neonatal intensive care unit | 167 | 304 | 0.98 (0.56 to 1.71) | 0.94 | NA |
| Shoulder dystocia | 163 | 235 | 0.90 (0.06 to 14.14) | 0.94 | NA |
| Birth trauma | 0 | — | — | — | — |
| Respiratory distress syndrome | 0 | — | — | — | — |
| Infant hypoglycaemia | 257 63 | 269 | 2.35 (0.47 to 11.76) | 0.3 | 0 |
| Infant hyperbilirubinaemia | 0 | — | — | — | — |
| All interventions | |||||
| Intrauterine death | 2 | 1320 | 0.15 (0.02 to 1.20) | 0.07 | 0 |
| Admission to neonatal intensive care unit | 3 | 2266 | 1.00 (0.75 to 1.33) | 1.00 | 58 |
| Shoulder dystocia | 4 | 2317 | 0.39 (0.22 to 0.70) | 0.002 | 0 |
| Birth trauma | 2 | 1961 | 0.36 (0.11 to 1.23) | 0.10 | 0 |
| Respiratory distress syndrome | 2 | 1962 | 1.05 (0.48 to 2.28) | 0.91 | 58 |
| Infant hypoglycaemia | 5 | 2146 | 1.07 (0.85 to 1.35) | 0.55 | 10 |
| Infant hyperbilirubinaemia | 2 | 1898 | 0.84 (0.64 to 1.10) | 0.19 | 0 |
*No randomised studies evaluated effect of physical activity for above outcomes.
NA=not applicable.