Table 4

 Differences in primary outcomes between discontinuation and continuation study groups, after 25 weeks

Primary outcomeRegression coefficient*Standard errorP95% CI
Cornell scale
 Total score −2.89 0.940.003†−4.76 to −1.02
 Total score (baseline score <9) −3.36 0.940.001†−5.23 to −1.48
 Total score (baseline score ≥9) 2.20 1.860.251−1.68 to 6.09
 Mood score−0.73 0.370.054−1.47 to 0.01
 Non-mood score−1.89 0.850.028†−3.56 to −0.21
Neuropsychiatric inventory
 Total score−5.96 3.230.068−12.35 to 0.44
 Affective subsyndrome−2.25 1.000.027†−4.24 to −0.27
 Agitation subsyndrome−1.14 1.400.417−3.93 to 1.64
 Psychosis subsyndrome−0.56 0.890.527−2.32 to 1.19
 Apathy −0.48 0.720.507−1.90 to 0.94

Data calculated by linear multi level model analysis.

*Negative score indicates higher score on Cornell scale and neuropsychiatric inventory in the discontinuation group.

†P<0.05.