Table 4

 Model inputs for cost effectiveness analysis cervical colorectal cancer control in WHO sub-Saharan African sub-region AfrE and South East Asian sub-region SearD

VariableAssumptionData source
Efficacy of HPV vaccination against HPV genotypes 16 and 18100%Kim et al17
Cervical smear test:Goldie et al21
 Sensitivity of detecting low grade lesions0.60
 Specificity of detecting low grade lesions0.95
HPV DNA testing:Goldie et al21
 Sensitivity of detecting low grade lesions0.84
 Specificity of detecting low grade lesions0.88
Visual inspection with acid (VIA):Goldie et al21
 Sensitivity of detecting low grade lesions0.68
 Specificity of detecting low grade lesions0.85
Cervical smear + HPV DNA tests combined:Kim et al22
 Sensitivity of detecting low grade lesions0.94
 Specificity of detecting low grade lesions0.93
Disability weight for cervical cancer0.075Murray and Lopez12

HPV= human papillomavirus

Estimates of incidence and case fatality reductions derived from modelling the above data are listed in table A3.1 in appendix 3 on bmj.com.