Table 1

 Characteristics of studies included in meta-analysis of association of chocolate consumption with risk of cardiometabolic disorders

Study (setting)Intervention measuresStudy designQuality score*ParticipantsFollow-up (years)Outcome measures
No in analysisCharacteristics
Oba et al 201016 (Japan)Consumption of coffee, tea, chocolate snacks, and caffeine contentCohort513 540Asian men and women10Incidence of diabetes
Mink et al 200714 (USA)Flavonoid intakeCohort534 489White postmenopausal women16Coronary heart disease, stroke, cardiovascular mortality
Janszky et al 200913 (Sweden)Chocolate consumptionCohort41169White men and women who had had an acute myocardial infarction8Cardiovascular mortality, recurrent myocardial infarction, stroke, congestive heart failure
Buijsse et al 20067 (Netherlands)Cocoa intakeCohort5470White men15Blood pressure, cardiovascular mortality
Mostofsky et al 201015 (Sweden)Chocolate intakeCohort531 823Middle aged and elderly white women9Incidence of heart failure
Buijsse et al 20109 (Germany)Chocolate consumptionCohort519 357White men and women10Blood pressure, myocardial infarction, incident cardiovascular disease, stroke
Djousse et al 201010 (USA)Chocolate consumptionCross sectional54970Men and women of mixed ethnicityNACoronary heart disease

*Score 0-6, with 6 representing high quality.