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  1. Randomised controlled...
  2. Randomised controlled factorial trial of dietary advice for patients with a single high blood pressure reading in primary care
Primary Care

Randomised controlled factorial trial of dietary advice for patients with a single high blood pressure reading in primary care

BMJ 2004; doi: https://doi.org/10.1136/bmj.38037.435972.EE (Published 13 April 2004) Cite this as: BMJ 2004;:bmj;bmj.38037.435972.EEv1

Data supplement

  • Table A

    Table B
     
     
     
     

    Table A Changes from baseline at one month in separate groups. Values are means (95% confidence intervals)
     

    OutcomeWhole cohort (n=269) Booklet + low sodium salt + prompts (n=32)Booklet + low sodium salt (n=32)Booklet + prompts (n=40) Booklet (n=38) Prompts + low sodium salt (n=31) Low sodium salt (n=30) Prompts (n=31)Control (n=35)
    Blood pressure (mm Hg)*:         
    Systolic (n=268)- 3.3 (- 1.8 to 4.9)- 0.71 (- 6.0 to 4.6)- 4.8 (- 0.15 to - 9.40)- 1.9 (- 5.7 to 1.8)- 4.2 (- 7.6 to - 0.85)0.19 (- 4.5 to 4.9)- 6.0 (- 12 to 0.24)- 3.2 (- 8.2 to 1.9)- 6.0 (- 10.3 to - 1.8)
    Diastolic (n=268)- 2.9 (- 1.9 to - 3.9)- 3.9 (- 0.4 to 7.4)- 4.6 (- 7.96 to - 1.14)- 1.1 (- 3.8 to 1.6)- 2.4 (- 4.7 to - 0.21)- 1.9 (- 5.1 to 1.3)- 1.9 (- 5.1 to 1.3)- 4.0 (- 6.8 to - 1.3)- 3.9 (- 6.7 to - 1.1)
    Weight (kg) (n=264)- 0.31 (- 0.07 to 0.54)- 0.42 (0.32 to - 1.17)- 0.19 (- 0.84 to 0.46)- 0.28 (- 0.80 to 0.23)0.33 (- 0.44 to 1.1)- 0.62 (- 1.4 to 0.14)- 0.39 (- 0.98 to 0.20)- 0.86 (- 01.6 to 0.15)- 0.15 (- 0.85 to 0.55)
    Cholesterol:HDL ratio (n=246)- 0.04 (- 0.12 to 0.05)- 0.01 (0.24 to - 0.26)0.10 (- 0.05 to 0.24)0.12 (- 0.13 to 0.36)- 0.14 (- 0.33 to 0.06)- 0.15 (- 0.47 to 0.16)- 0.03 (- 0.30 to 0.24)- 0.22 (- 0.60 to 0.16)0.03 (- 0.22 to 0.28)
    Low density lipoprotein (n=204)- 0.07 (- 0.14 to 0.01)- 0.13 (- 0.35 to 0.10)- 0.03 (- 0.24 to 0.17)0.01 (- 0.19 to 0.21)- 0.11 (- 0.29 to 0.06)- 0.11 (- 0.37 to 0.15)0.11 (- 0.14 to 0.35)- 0.20 (- 0.42 to 0.02)0.05 (- 0.28 to 0.16)
    Carotenoid concentration (mmol/l) (n=235)100 (50 to 151)192 (- 33 to 418)50 (- 72 to 173)126 (- 18 to 270)139 (- 7 to 286)39 (- 79 to 156)- 18 (- 107 to 71)68 (- 100 to 236)180 (62 to 300)
    Na:K ratio (n=260)- 0.31 (- 0.14 to - 0.48)- 0.60 (- 1.27 to 0.08)- 0.37 (- 0.83 to 0.08)0.19 (- 0.24 to 0.62)- 0.27 (- 0.64 to 0.10)- 0.47 (- 1.04 to 0.10)- 0.46 (- 1.1 to 0.14)0.06 (- 0.40 to 0.28)0.57 (- 1.13 to - 0.08)
    Food frequency questionnaire:         
    Total fat (g/day )(n=219)- 12.1 (- 6.2 to 18.1)- 25.4 (- 9.3 to - 41.4)- 9.0 (- 21.9 to 4.0)- 16.4 (- 33.8 to 0.9)- 3.2 (- 19.7 to 13.2)- 23.6 (- 44.0 to - 3.2)- 19.4 (- 4.1 to - 34.6)- 11.6 (- 28.0 to 4.8)9.7 (- 12 to 31)
    % energy from fat (n=202)- 3.1 (- 2.0 to - 4.1)- 4.7 (- 8.9 to - 0.53)- 2.9 (- 5.1 to - 0.68)- 3.4 (- 5.7 to - 1.0)- 2.3 (- 4.8 to 0.25)- 4.3 (- 7.9 to - 0.59)- 1.2 (- 4.9 to 2.6)- 3.4 (- 7.1 to 0.26)- 2.7 (- 0.28 to - 5.13)
    Non-starch polysaccharide (g/day) (n=202)1.4 (0.2 to 2.6)4.1 (1.3 to 6.9)2.3 (- 1.9 to 6.5)0.85 (- 1.9 to 3.6)2.0 (- 1.9 to 5.9)0.13 (- 3.9 to 3.7)- 3.2 (- 6.7 to 0.35)3.9 (0.64 to 7.2)1.5 (- 1.7 to 4.7)
    Fruit and vegetables (g/day) (n=219)90 (56 to 123)170 (95 to 246)42 (- 86 to 169)124 (48 to 201)82 (12 to 152)97 (11 to 183)- 80 (- 166 to 6)220 (90 to 348)63 (- 31 to 157)
    Anxiety (hospital anxiety and depression scale) (n=219)0.07 (- 0.14 to 0.29)- 0.33 (- 1.2 to 0.52)0.43 (- 0.10 to 0.96)- 0.65 (- 1.1 to 0.19)0.72 (0.16 to 1.3)0.30 (- 0.24 to 0.85)0.48 (- 0.29 to 1.2)- 0.26 (- 1.0 to 0.53)- 0.08 (- 0.60 to 0.45)

    HDL=high density lipoprotein.

    Numbers for outcomes vary due to missing values.
     
     
     

    Table B Changes from baseline at six months in separate groups. Values are means (95% confidence intervals)
     

    Outcome
    Whole cohort (n=245) 
    Booklet + low sodium salt + prompts (n=28)
    Booklet + low sodium salt (n=27)
    Booklet + prompts (n=36)
    Booklet (n=37)
    Prompts + low sodium salt (n=30)
    Low sodium salt (n=30)
    Prompts (n=27)
    Control (n=30)
    Blood pressure (mm Hg):         
    Systolic (n=244)
    - 5.0 (- 3.1 to 7.0)
    - 4.0 (- 8.7 to - 0.56)
    - 3.7 (- 9.6 to 2.3)
    - 5.2 (- 10.4 to - 0.03)
    - 3.5 (- 8.3 to 1.3)
    - 2.5 (- 8.5 to 3.59)
    - 6.4 (- 0.52 to - 12.3)
    - 4.7 (- 12.6 to 3.1)
    - 10.3 (- 15.8 to - 4.8)
    Diastolic (n=244)
    - 3.2 (- 4.3 to - 2.1)
    - 2.1 (- 4.2 to 0.0)
    - 2.0 (- 5.6 to 1.6)
    - 3.6 (- 6.5 to - 0.69)
    - 4.4 (- 4.7 to 0.95)
    - 2.8 (- 6.7 to 0.97)
    - 1.7 (- 5.2 to 1.8)
    - 3.3 (- 7.2 to 0.65)
    - 5.1 (- 8.2 to - 2.0)
    Weight (kg) (n=240)
    - 0.31 (- 0.86 to 0.23)
    0.00 (- 1.54 to 1.54)
    0.98 (- 2.3 to 4.3)
    - 1.8 (- 3.26 to - 0.37)
    0.39 (- 0.48 to 1.3)
    - 0.58 (- 1.7 to 0.55)
    - 0.42 (- 1.7 to 0.80)
    - 1.1 (- 2.8 to 0.63)
    0.20 (- 0.54 to 0.93)
    Cholesterol:HDL ratio (n=246)
    - 0.03 (- 0.13 to 0.06)
    - 0.01 (- 0.28 to 0.26)
    0.20 (- 0.07 to 0.47)
    - 0.03 (- 0.23 to 0.30)
    - 0.15 (- 0.38 to 0.08)
    - 0.16 (- 0.50 to 0.17)
    - 0.21 (- 0.47 to 0.05)
    - 0.16 (- 0.44 to 0.11)
    0.30 (0.03 to 0.56)
    Low density lipoprotein (n=204)
    0.00 (- 0.08 to 0.08)
    - 0.14 (- 0.40 to 0.11)
    0.07 (- 0.21 to 0.36)
    - 0.09 (- 0.29 to 0.10)
    - 0.05 (- 0.29 to 0.18)
    0.10 (- 0.12 to 0.32)
    0.11 (- 0.12 to 0.35)
    - 0.05 (- 0.33 to 0.24)
    0.09 (- 0.19 to 0.37)
    Carotenoid concentration (mmol/l) (n=235)
    130 (58 to 202)
    106 (- 141 to 353)
    124 (- 3 to 251)
    263 (56 to 470)
    143 (- 63 to 349)
    156 (- 30 to 342)
    35 (- 226 to 296)
    137 (- 131 to 404)
    39 (- 140 to 218)
    Na:K ratio (n=260)
    - 0.21 (- 0.39 to - 0.03)
    - 0.15 (- 0.84 to 0.54)
    - 0.32 (- 0.74 to 0.09)
    0.22 (- 0.35 to 0.78)
    - 0.41 (- 0.88 to 0.06)
    - 0.36 (- 0.78 to 0.07)
    - 0.22 (- 0.77 to 0.32)
    0.18 (- 0.28 to 0.62)
    - 0.56 (- 1.2 to 0.08)
    Food frequency questionnaire:         
    Total fat (g/day) (n=219)
    - 9.6 (- 15.8 to - 3.3)
    - 17.4 (- 32.7 to - 2.0)
    4.3 (- 14.0 to 5.5)
    - 20.9 (- 36.4 to - 5.5)
    - 7.5 (- 26.9 to 11.9)
    - 18.1 (- 36.0 to - 0.2)
    0.33 (- 27.9 to 27.3)
    - 0.99 (- 24.5 to 22.5)
    - 4.4 (- 15.0 to 6.2)
    % energy from fat (n=202)
    - 2.4 (- 1.3 to - 3.5)
    - 3.4 (- 0.40 to - 6.4)
    - 2.5 (- 5.7 to 0.8)
    - 4.0 (- 2.2 to - 5.9)
    - 0.03 (- 2.9 to 2.9)
    - 3.2 (- 6.9 to 0.55)
    - 1.2 (- 5.3 to 2.8)
    - 2.0 (- 5.6 to 1.8)
    - 2.9 (- 6.3 to 0.53)
    Non-starch polyssacharide (g/day) (n=202)
    1.2 (- 0.01 to 2.3)
    3.1 (0.45 to 5.7)
    1.3 (- 1.5 to 4.1)
    1.5 (- 1.4 to 4.4)
    - 0.22 (- 3.5 to 3.1)
    - 0.43 (- 4.5 to 3.6)
    0.57 (- 4.7 to 3.6)
    4.9 (1.1 to 8.7)
    0.82 (- 3.0 to 4.6)
    Fruit and vegetables (g/day) (n=219)
    86 (53 to 119)
    156 (65 to 246)
    66 (- 62 to 194)
    122 (36 to 210)
    127 (58 to 196)
    6 (- 78 to 66)
    42 (- 150 to 66)
    183 (74 to 292)
    80 (- 20 to 181)
    Anxiety (hospital anxiety and depression scale) (n=202)
    0.0 (- 0.25 to 0.24)
    - 0.38 (- 1.3 to 0.51)
    0.20 (- 0.55 to 0.95)
    - 0.30 (- 0.97 to 0.37)
    0.83 (0.21 to 1.5)
    - 0.13 (- 0.73 to 0.47)
    - 0.05 (- 0.90 to 0.80)
    - 0.09 (- 0.75 to 0.56)
    - 0.31 (- 0.97 to 0.36)

    HDL=high density lipoprotein.

    Numbers for outcomes vary due to missing values.
     
     
     
     
     
     

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