Systematic review of the incidence and consequences of uterine rupture in women with previous caesarean section
BMJ 2004; 329 doi: https://doi.org/10.1136/bmj.329.7456.19 (Published 01 July 2004) Cite this as: BMJ 2004;329:19Data supplement
(Posted as supplied by authors)
Uterine Rupture: Supplementary Table of Included Studies
Study
Purpose of Study
Population
Sample Size
Uterine exploration
Reported outcomes
Reported associated major morbidty
Meehan
198918
Compare risk between of trial of labor and planned cesarean delivery after a previous cesarean.
TOL-One prior CD
ERCD- One or more prior CDs
I- 127
A- 217
SL- 162
ERCD- 430
NR
Symptomatic UR: TOL- 1
Asymptomatic UR: TOL- 5
Symptomatic UR: 0 perinatal deaths
0 maternal deaths
Blanchette
199923
To compare PGE1 (misoprostol) to PGE2 (dinoprostone) for cervical ripening and induction in a community hospital.
One or more LTCD, not clear what was done with unknown
PGE1- 16
PGE2- 9
NR
Symptomatic UR: PGE1- 3
Symptomatic UR: PGE2- 0
Symptomatic UR: PGE1- 0 maternal deaths, 1 perinatal death, 3 hysterectomies
Flamm
198724
To compare the use of oxytocin for trial of labor in patients with one or more previous cesarean deliveries.
LTCD and unknown and more than 1 prior
IA- 485
SL- 1291
NR
Symptomatic UR: IA- 2
SL- 1
Asymptomatic UR: IA-5
SL- 6
Symptomatic UR: Overall- 0 maternal deaths, insufficient detail for UR-related perinatal deaths or hysterectomies
Flamm
199725
Evaluate the use of PGE2 for cervical ripening in patients with prior CD
LTCD and unknown and more than 1 prior
IA- 453
SL-4569
Discretion
Symptomatic UR: IA- 6
SL- 33
Symptomatic UR: Overall- Insufficient detail for UR-related maternal deaths, perinatal deaths, or hysterectomies
Blanco
199226
Determine safety and efficacy of induction with PGE2 in patients with a prior low transever CD
One prior LTCD
IA- 25
SL- 56
NR
Symptomatic UR: IA-0
SL- 0
Asymptomatic UR: IA- 0
SL- 0
NA
Connolly
200127
Identify risk factors for scar dehiscence in labor.
Cases: 1 prior LTCD or low vertical CD who underwent TOL with dehiscence
Controls: one prior LTCD or low vertical CD who underwent TOL without dehiscence
Cases: 13
Controls: 13
NR
8 partial dehiscence
5 complete dehiscence
0 maternal deaths, 0 perinatal deaths, 0 hysterectomies
Leung
199328
Identify risk of uterine rupture in a trial of labor after a previous cesarean delivery.
Cases: patients with prior CD and UR while undergoing subsequent TOL
Controls: patients with prior CD and subsequent TOL and no UR during same time, randomly selected, grouped by year
(More than one and unknown allowed)
Cases: 70
Controls: 70
Yes
Symptomatic UR: 70
NR
Leung
199329
Identify risk factors associated with overt, catastrophic uterine rupture after previous cesarean delivery.
Case series of all cases of uterine rupture after a previous cesarean delivery
99 URs
NR
Symptomatic UR: 99
Symptomatic UR: 1 maternal death, 6 perinatal deaths, 19 hysterectomies, 29 transfusions.
Bujold
200230
Evaluate factors associated with neonatal disease and death caused by uterine rupture in patients undergoing a trial of labor after previous cesarean delivery.
Case series of symptomatic UR
following TOL after LTCD
23 Urs
NR
Symptomatic UR: 23
Symptomatic UR: 1 perinatal death, 3 hypoxicischemic encephalopathies
Smith
200211
Determine risk of intrapartum still birth or neonatal death between trial of labor after previous cesarean delivery and planned repeat cesarean delivery.
Singleton pregnancies between 37-42 weeks, cephalic, without lethal congenital anomalies, one or more prior CD, not clear what was done with unknown and low vertical
SL/IA- 15515
ERCD- 9014
NR
NA
Perinatal Death due to mechanical-TOL- 7
ERCD- 0
Mechanical-uterine rupture, cord compression (including prolapse), birth trauma, or asphysixa associated with disproportion.
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