Trigger factors and HL-A antigens in chronic active hepatitisBr Med J 1975; 4 doi: https://doi.org/10.1136/bmj.4.5988.77 (Published 11 October 1975) Cite this as: Br Med J 1975;4:77
- Johan Lindberg,
- Annika Lindholm,
- Per Lundin,
- Sten Iwarson
Forty-six patients with histologically verified chronic active hepatitis (CAH) were divided into three groups according to whether the CAH was virus-induced, drug-induced, or cryptogenic. The frequency of the HL-A antigens 1 and 8 was increased in the cryptogenic group while the other groups did not differ significantly from healthy controls. Autoantibodies were often found in high titres in the drug-induced and cryptogenic groups but were infrequent in the virus-induced group.