Papers And Originals

Effect of a Millipore Filter on Complications of Intravenous Infusions: A Prospective Clinical Trial

Br Med J 1973; 4 doi: https://doi.org/10.1136/bmj.4.5890.456 (Published 24 November 1973) Cite this as: Br Med J 1973;4:456
  1. J. Collin,
  2. D. E. F. Tweedle,
  3. C. W. Venables,
  4. F. L. Constable,
  5. Ivan D. A. Johnston

    Abstract

    The Millipore filter unit has been advocated as a means of reducing the chance of bacteria entering the circulation during intravenous infusion. In a prospective study no significant reduction was obtained in the incidence of thrombophlebitis or in the bacterial contamination of cannulae. The unit was inconvenient to use and in-vitro and in-vivo studies showed reduced flow rates and frequent episodes of filter blockage. Its use was further restricted by the fact that blood and fat emulsions would not pass through it.