Papers And Originals

Early Clinical Experience with Bleomycin in the United Kingdom in Series of 105 Patients

Br Med J 1972; 4 doi: http://dx.doi.org/10.1136/bmj.4.5841.635 (Published 16 December 1972) Cite this as: Br Med J 1972;4:635
  1. K. E. Halnan,
  2. N. M. Bleehen,
  3. T. B. Brewin,
  4. T. J. Deeley,
  5. D. F. N. Harrison,
  6. C. Howland,
  7. P. B. Kunkler,
  8. G. L. Ritchie,
  9. E. Wiltshaw,
  10. I. D. H. Todd

    Abstract

    The results of treating a series of 105 patients (79 with advanced squamous cell carcinoma, 21 with advanced lymphoma, and 5 with miscellaneous tumours) with bleomycin are described. The drug was usually given as a single agent. Four patients with squamous cell carcinoma showed complete regression and there was partial regression in 25. Side effects were frequent, particularly skin changes and stomatitis; death from pneumonitis occurred in one patient.