Glucose Tolerance and Insulin Secretion in Patients with Chronic Duodenal UlcerBr Med J 1972; 4 doi: http://dx.doi.org/10.1136/bmj.4.5837.393 (Published 18 November 1972) Cite this as: Br Med J 1972;4:393
- C. S. Humphrey,
- J. R. W. Dykes,
- D. Johnston
An oral glucose tolerance test has been used to compare carbohydrate metabolism in patients suffering from chronic duodenal ulceration with that in a matched group of normal subjects. A significantly greater rise in blood glucose concentration was observed in the duodenal ulcer group, and this was associated with a significantly greater output of insulin. The reason for these findings may be an abnormal secretion of one or more of the small-bowel hormones.