Papers And Originals

Glucose Tolerance and Insulin Secretion in Patients with Chronic Duodenal Ulcer

Br Med J 1972; 4 doi: https://doi.org/10.1136/bmj.4.5837.393 (Published 18 November 1972) Cite this as: Br Med J 1972;4:393
  1. C. S. Humphrey,
  2. J. R. W. Dykes,
  3. D. Johnston

    Abstract

    An oral glucose tolerance test has been used to compare carbohydrate metabolism in patients suffering from chronic duodenal ulceration with that in a matched group of normal subjects. A significantly greater rise in blood glucose concentration was observed in the duodenal ulcer group, and this was associated with a significantly greater output of insulin. The reason for these findings may be an abnormal secretion of one or more of the small-bowel hormones.