Papers And Originals

Lymphocytotoxins in Leukaemia

Br Med J 1972; 4 doi: https://doi.org/10.1136/bmj.4.5834.209 (Published 28 October 1972) Cite this as: Br Med J 1972;4:209
  1. Ann Dickson

    Abstract

    Fifteen out of 51 patients with leukaemia have produced a lymphocytotoxin in their serum which reacts with their own and a high percentage of all other lymphocytes. This is probably a protein, but not an antibody. It has been detected only before or early during cytotoxic treatment, or during a relapse. It is postulated that the lymphocytotoxin is a specific protein produced by the leukaemic cells, which may facilitate their spread in the body.