Papers And Originals

Primary Hepatoma and Hepatitis-associated Antigen in a Young White Woman

Br Med J 1972; 4 doi: (Published 21 October 1972) Cite this as: Br Med J 1972;4:149
  1. E. C. Campion,
  2. J. Ludbrook,
  3. G. M. McLeod,
  4. V. R. Marshall,
  5. Tapen Mukheriee,
  6. A. G. Wangel


    A young woman whose serum was positive for hepatitis-associated antigen (H.A.A.) and alpha-fetoprotein developed a malignant hepatoma. Though the light-microscopical appearances of the surrounding liver tissue were normal, electronmicroscope examination of the tumour tissue disclosed both C-virus-like particles and H.A.A. particles. Possibly there was a causal connexion between one of these particles and the hepatoma.