Papers And Originals

Platelet Defect of Infectious Mononucleosis

Br Med J 1971; 4 doi: https://doi.org/10.1136/bmj.4.5788.646 (Published 11 December 1971) Cite this as: Br Med J 1971;4:646
  1. Robert Clancy,
  2. Elizabeth Jenkins,
  3. Barry Firkin

    Abstract

    Platelet function has been studied in 16 patients with uncomplicated infectious mononucleosis. Some abnormality of platelet aggregation and/or release of platelet factor III or platelet factor IV was found in all patients. Six patients with platelet defects were retested after three to four months and were found to have normal platelet function and appreciably higher platelet counts. Abnormal platelet function may reflect a platelet defect which predisposes to premature platelet destruction. Recent viral illness should be excluded before attributing abnormal platelet function to other factors or to a congenital disorder.