Use of”Tcm for the Routine Assessment of Thyroid FunctionBr Med J 1971; 4 doi: http://dx.doi.org/10.1136/bmj.4.5784.396 (Published 13 November 1971) Cite this as: Br Med J 1971;4:396
- A. W. G. Goolden,
- H. I. Glass,
- E. D. Williams
99Tcm-pertechnetate is concentrated in the thyroid in the same way as iodide but it does not become organically bound. The uptake of 99Tcm is a measure of the thyroid trap, and this measurement is satisfactory as a routine test in the diagnosis of thyrotoxicosis. The reproducibility of the method is such that suppression tests can be carried out when necessary even when uptake is within the normal range of 0·4-3%. 99Tcm gives a low radiation dose to the thyroid and has certain other advantages over radioactive isotopes of iodine for early thyroid uptake measurements. It is particularly suitable when serial tests of thyroid function are required during treatment with an antithyroid drug.