Nephrotic Syndrome in Monkey Infected with Human Quartan MalariaBr Med J 1971; 4 doi: https://doi.org/10.1136/bmj.4.5781.208 (Published 23 October 1971) Cite this as: Br Med J 1971;4:208
- A. Voller,
- C. C. Draper,
- Tin Shwe,
- M. S. R. Hutt
A splenectomized aotus monkey infected with human quartan malaria (Plasmodium malariae) developed oedema and proteinuria. Histological examination revealed a generalized diffuse glomerulonephritis and immunofluorescent staining showed granular deposits of IgM in the glomeruli. The pathological picture resembled that shown by human patients with the quartan malaria nephrotic syndrome.