Papers And Originals

Nephrotic Syndrome in Monkey Infected with Human Quartan Malaria

Br Med J 1971; 4 doi: https://doi.org/10.1136/bmj.4.5781.208 (Published 23 October 1971) Cite this as: Br Med J 1971;4:208
  1. A. Voller,
  2. C. C. Draper,
  3. Tin Shwe,
  4. M. S. R. Hutt

    Abstract

    A splenectomized aotus monkey infected with human quartan malaria (Plasmodium malariae) developed oedema and proteinuria. Histological examination revealed a generalized diffuse glomerulonephritis and immunofluorescent staining showed granular deposits of IgM in the glomeruli. The pathological picture resembled that shown by human patients with the quartan malaria nephrotic syndrome.