Papers And Originals

Folic Acid in Folate-deficient Patients with Epilepsy

Br Med J 1970; 4 doi: https://doi.org/10.1136/bmj.4.5736.644 (Published 12 December 1970) Cite this as: Br Med J 1970;4:644
  1. Richard H. E. Grant,
  2. Olga P. R. Stores

    Abstract

    A double-blind trial using folic acid 15 mg. daily and identical placebo was carried out in 51 epileptic patients having a serum folate level below 3·6 ng./ml. Treatment was for a minimum of six months and in 41 patients was for more than one year. There were no significant changes in the frequency of seizures, behaviour, and personality, or in a number of cognitive functions.