Papers And Originals

Idiopathic Hypercalciuria and Hyperparathyroidism

Br Med J 1970; 4 doi: (Published 05 December 1970) Cite this as: Br Med J 1970;4:582
  1. Peter Adams,
  2. T. M. Chalmers,
  3. L. F. Hill,
  4. B. McN Truscott


    With provocative tests of parathyroid activity based on phosphate deprivation and the administration of chlorothiazide 8 out of 19 patients with idiopathic hypercalciuria developed hypercalcaemia. Five of the eight underwent exploration of the neck and four of them had parathyroid adenomas; the fifth patient had “normal” glands but responded satisfactorily to subtotal parathyroidectomy. One patient who failed to develop hypercalcaemia had primary chief cell hyperplasia of the parathyroids.