Papers And Originals

Latent cytomegalovirus infection in blood donors

Br Med J 1969; 4 doi: (Published 13 December 1969) Cite this as: Br Med J 1969;4:660
  1. Peter Diosi,
  2. Eva Moldovan,
  3. Nicholas Tomescu


    Twenty-one out of 32 apparently healthy blood donors aged 21 to 65 years yielded positive complement fixation tests with a cytomegalovirus antigen, at titres ranging from 1:8 to 1:64. Virus was present in leucocyte cultures of fresh peripheral blood of two seropositive subjects from a total of 35 donors examined. Plasma and 48-hour stored blood specimens failed to disclose virus in culture. Viruria could not be demonstrated, and there was no evidence of recent illness in the study group. These findings suggest that subclinical viraemia is not uncommon in blood donors.