Papers And Originals

Immunological studies in tropical splenomegaly syndrome in Uganda

Br Med J 1969; 4 doi: https://doi.org/10.1136/bmj.4.5674.15 (Published 04 October 1969) Cite this as: Br Med J 1969;4:15
  1. John L. Ziegler,
  2. Martin H. Cohen,
  3. M. S. R. Hutt

    Abstract

    An immunological evaluation carried out in eight patients with the tropical splenomegaly syndrome showed no evidence of impairment in cellular or humoral immunity, though raised levels of macroglobulins were noted in four patients. Hence gross immunological deficiency cannot be associated with the intense lymphoreticular proliferation observed in this disorder.