Papers And Originals

Appearance of Prostaglandin F2α in Human Blood during Labour

Br Med J 1968; 4 doi: https://doi.org/10.1136/bmj.4.5631.618 (Published 07 December 1968) Cite this as: Br Med J 1968;4:618
  1. S. M. M. Karim

    Abstract

    Blood samples from over 70 pregnant women have been examined for the presence of four prostaglandins. Samples obtained from women not in labour at different gestation periods and at term contained no detectable amounts of prostaglandins. Prostaglandin F was present in samples of blood obtained during normal spontaneous labour. The appearance of this substance in the blood preceded the uterine contraction. Whether prostaglandins play a part in the process of normal labour is still conjectural.

    Footnotes

    • * Part of the work presented in this paper was carried out at the Institute of Obstetrics and Gynaecology, Queen Charlotte's Maternity Hospital, London W.6.