Papers And Originals

Fatal Brain Damage Associated with Cardiomyopathy of Pregnancy, with Notes on Caesarean Section in a Hyperbaric Chamber

Br Med J 1968; 4 doi: (Published 02 November 1968) Cite this as: Br Med J 1968;4:285
  1. I. McA. Ledingham,
  2. T. I. McBride,
  3. W. B. Jennett,
  4. J. Hume Adams,
  5. S. A. P. Tindal


    Three weeks after admission to a maternity hospital for observation following minor antepartum haemorrhage, a primiparous patient aged 22 suffered a sudden left hemiplegia and became comatose. Congestive cardiac failure ensued and because of the subsequent severe hypoxaemia she was transferred to the hyperbaric oxygen unit at the Western Infirmary, Glasgow, where it was found possible to improve her condition by means of oxygen at increased pressure. A caesarean section was w successfully performed in the hyperbaric chamber, and a normal live female infant was delivered. Though the patient's general condition improved she never regained consciousness and died almost three months later. Necropsy confirmed the clinical diagnosis of cardiomyopathy of pregnancy with severe ischaemic changes in the brain.