Proton pump inhibitor use does not raise dementia and Alzheimer’s risk, study suggests

A US study1 has not confirmed earlier reports that proton pump inhibitor (PPI) use is linked to an increased risk of dementia and Alzheimer’s disease.2 In contrast, the latest study, published in the Journal of the American Geriatrics Society,1 found that continuous or intermittent PPI use was associated with a lower risk of cognitive decline.

Using the National Alzheimer’s Coordinating Center database covering 2005-15 the researchers identified patients aged over 50 who had normal cognition or mild cognitive impairment (with cognitive test scores lower than normal …