Levothyroxine shows no benefit in elderly patients with subclinical hypothyroidism, trial findsBMJ 2017; 357 doi: https://doi.org/10.1136/bmj.j1754 (Published 06 April 2017) Cite this as: BMJ 2017;357:j1754
- Susan Mayor
Treatment with levothyroxine provides no clinical benefit in older people with subclinical hypothyroidism, a UK randomised trial published in the New England Journal of Medicine has shown.1
Subclinical hypothyroidism, defined as an elevated serum thyrotropin level and a serum free thyroxine level within the reference range, is common in older people, affecting 8-18% of over 65s. It is more common in women than men.
Thyroid hormones have a wide …