Letters Warfarin plus sulfonylureas and serious hypoglycemic events

Warfarin with sulfonylureas and hypoglycemic events: consider dose, length of treatment, and all sulfonylureas

BMJ 2016; 354 doi: https://doi.org/10.1136/bmj.i4328 (Published 05 August 2016) Cite this as: BMJ 2016;354:i4328
  1. Pauline Bosco-Lévy, clinical pharmacologist1,
  2. Francesco Salvo, clinical pharmacologist1
  1. 1Université de Bordeaux, UMR1219, CHU de Bordeaux, 146 Rue Léo Saignat, 33076 Bordeaux Cedex, France
  1. pauline.bosco-levy{at}u-bordeaux.fr

Romley and colleagues studied the association between the use of warfarin with common sulfonylureas and the development of serious hypoglycemic events.1 Data on potential interactions are essential because both drugs have a narrow therapeutic range and can also interact with many other drugs.2 3

The pharmacological effect of these drugs …

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