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Technique to eliminate mitochondrial disease carries very small risk of failure, researchers find

BMJ 2016; 353 doi: https://doi.org/10.1136/bmj.i3288 (Published 10 June 2016) Cite this as: BMJ 2016;353:i3288
  1. Jilna Shukla
  1. The BMJ

A team of researchers from Newcastle, UK, have described a new technique that may reduce the risk of serious inherited diseases, although they warned of a small risk that the procedure will fail.

Last February the United Kingdom became the first country in the world to allow mitochondrial donation to prevent serious genetic inherited diseases, after the House of Lords voted in favour of a change in the law to permit new in vitro fertilisation (IVF) techniques.1 The researchers at Newcastle, led by Mary Herbert and Doug Turnbull, have become the first to develop a method called pronuclear transfer (PNT).2

About one person in 10 000 …

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