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Lamotrigine for epilepsy may not increase risk of birth defects, study shows

BMJ 2016; 353 doi: https://doi.org/10.1136/bmj.i1965 (Published 07 April 2016) Cite this as: BMJ 2016;353:i1965
  1. Jacqui Wise
  1. London

Babies born to pregnant women who are taking the epilepsy drug lamotrigine seem not to be at increased risk of birth defects such as cleft lip, cleft palate, or club foot, research published in Neurology has shown.1

Lamotrigine is a commonly used treatment for epilepsy and bipolar disorder. Maintaining epilepsy treatment during pregnancy is important because seizures may harm the fetus. The Medicines and Healthcare Products Regulatory Agency added a warning about the specific risk of …

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