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Testosterone may improve sexual function and mood in older men with low levels

BMJ 2016; 352 doi: https://doi.org/10.1136/bmj.i989 (Published 18 February 2016) Cite this as: BMJ 2016;352:i989
  1. Susan Mayor
  1. London

Treatment with testosterone improved sexual function and mood in men aged over 65 with low levels of the hormone but had no effect on physical functioning or vitality, a randomised trial has shown.1 But researchers warned that larger studies are needed to adequately assess any potential risks from this therapy.

Serum concentrations of testosterone fall with age, but the benefits of raising testosterone levels in older men have not previously been demonstrated as trials have given equivocal results.

Reviewing the issue in 2003, the Institute of Medicine found insufficient evidence that testosterone treatment was beneficial in older men and recommended that trials should assess the effect of raising …

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