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Higher oxygen saturation targets are safer for preterm infants, trials show

BMJ 2016; 352 doi: https://doi.org/10.1136/bmj.i852 (Published 11 February 2016) Cite this as: BMJ 2016;352:i852
  1. Susan Mayor,
  2. London

Using lower oxygen saturation targets when treating preterm infants is associated with a higher risk of death and disability at 2 years than with higher targets, the combined results of two large randomised trials have shown.1

The safest ranges for oxygen saturation that most effectively minimise the risks of death, retinopathy, and later disability in preterm infants have been hotly debated. Two trials, one in Australia and the second in the United Kingdom, randomly allocated …

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