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Co-trimoxazole in addition to antiretroviral therapy may reduce malaria risk in HIV positive adults

BMJ 2016; 352 doi: https://doi.org/10.1136/bmj.i49 (Published 06 January 2016) Cite this as: BMJ 2016;352:i49
  1. Nigel Hawkes
  1. 1London

In malaria endemic regions people with HIV infection who are treated with antiretroviral therapy do better if they are also given the antibiotic co-trimoxazole, a trial in Kenya has shown.1

Prophylactic use of co-trimoxazole has been recommended by the World Health Organization since 2006, but that guidance predated the widespread use of antiretroviral therapy, so it has not been clear whether it remained appropriate. The trial, by showing that mortality and morbidity were higher among those in whom …

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