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Low blood levels of bicarbonate are linked to premature death in healthy older people, study shows

BMJ 2016; 352 doi: https://doi.org/10.1136/bmj.i172 (Published 15 January 2016) Cite this as: BMJ 2016;352:i172
  1. Susan Mayor
  1. 1London

Low blood levels of bicarbonate, which helps to regulate the blood’s pH, are associated with increased risk of premature death in healthy older people, a 10 year follow-up study has found.1

Low serum bicarbonate is a known risk factor for mortality and progression in people with chronic kidney disease, but its role in kidney function and mortality in healthy people is less clear.

To investigate this question, researchers analysed data on pH, carbon dioxide, and bicarbonate levels in blood samples from 2287 healthy …

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