Letters Cardiovascular outcomes with clarithromycin

Study provides insufficient evidence of a link between clarithromycin and myocardial infarction

BMJ 2016; 352 doi: https://doi.org/10.1136/bmj.i1342 (Published 08 March 2016) Cite this as: BMJ 2016;352:i1342
  1. Zac Blake, GP registrar
  1. Norwich, UK
  1. zac.blake{at}doctors.org.uk

As a GP registrar who regularly prescribes antibiotics, I read Wong and colleagues’ paper on clarithromycin and cardiovascular outcomes and the associated editorial with interest.1 2

I disagree with the editorial in that the study contains only two, not three, separate study designs.

My main concern with the paper is that the second study design simply shows, using two statistical methods, that people with …

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