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Intensive blood pressure control reduces cardiovascular events, studies show

BMJ 2015; 351 doi: (Published 10 November 2015) Cite this as: BMJ 2015;351:h6022
  1. Susan Mayor
  1. 1London

Intensive blood pressure reduction significantly reduces numbers of major cardiovascular events in people at high risk of cardiovascular events, when compared with standard blood pressure control, but at the cost of more adverse events, show a randomised trial and a meta-analysis.1 2 The results provide evidence for lowering blood pressure targets in some people, the researchers argued.

The trial, reported in the New England Journal of Medicine, randomised 9361 people with a systolic blood pressure of 130 mm Hg or higher and increased cardiovascular risk but without diabetes to intensive or standard blood pressure lowering. The target was a systolic blood pressure of less than 120 mm Hg in the intensive treatment group and less than 140 mm Hg in the standard treatment group.

The US …

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