Astonishing things in cardiovascular medicine and other stories . . .

BMJ 2015; 351 doi: https://doi.org/10.1136/bmj.h4886 (Published 17 September 2015) Cite this as: BMJ 2015;351:h4886

Astonishing things are happening in cardiovascular medicine. As event rates plummet and presentations change, textbooks need to be thrown away faster than they can be rewritten. A record linkage study of nearly two million people without previous cardiovascular disease in the United Kingdom identified 114 859 who had cardiovascular events during six years’ median follow-up between 1997 and 2010 (Circulation 2015, doi:10.1161/CIRCULATIONAHA.114.013797). Two thirds of these events were neither myocardial infarction nor ischaemic stroke, two conditions to which preventive effort is overwhelmingly directed.

“Evidence based medicine: a movement in crisis?” was one of the most widely read and commented on Analysis pieces in The BMJ last year (BMJ 2014;348, doi:10.1136/bmj.g3725), and it has received 83 876 page views since its publication in June 2014. Now Trish Greenhalgh and colleagues are running a lively series in BMC Medicine called “Extending evidence-based medicine.” The first article discusses six important biases against patients and carers in evidence based medicine (2015;13:200, doi:10.1186/s12916-015-0437-x). These include …

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