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Corticosteroids reduce treatment failure in severe community acquired pneumonia, trial shows

BMJ 2015; 350 doi: https://doi.org/10.1136/bmj.h894 (Published 18 February 2015) Cite this as: BMJ 2015;350:h894
  1. Susan Mayor
  1. 1London

Corticosteroid therapy significantly reduces treatment failure in patients hospitalised with severe community acquired pneumonia who have high inflammatory response, a study has found.

Community acquired pneumonia is currently the leading cause of death from infectious disease in developed countries. Mortality is high in patients who are hospitalised with the condition, particularly in those with severe pneumonia and in the 10-20% whose treatment fails.

The trial, reported in JAMA,1 included 120 patients admitted to three Spanish teaching hospitals with severe community acquired …

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