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Zoledronic acid increases bone density but does not reduce fractures in frail elderly people, study finds

BMJ 2015; 350 doi: https://doi.org/10.1136/bmj.h1949 (Published 14 April 2015) Cite this as: BMJ 2015;350:h1949
  1. Zosia Kmietowicz
  1. 1The BMJ

A single intravenous dose of the osteoporosis drug zoledronic acid has been found to increase bone mineral density in a group of frail elderly women living in nursing homes and long term care facilities, but it did not reduce the incidence of fractures over a two year period.

Researchers from the University of Pittsburgh found that 85% of elderly people in long term care facilities had osteoporosis and fracture rates eight to nine times higher …

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