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Early trials of Ebola vaccine show immune response

BMJ 2015; 350 doi: https://doi.org/10.1136/bmj.h1844 (Published 08 April 2015) Cite this as: BMJ 2015;350:h1844
  1. Susan Mayor
  1. 1London

Small, phase I trials in Africa and Europe of an experimental vaccine against Ebola virus disease have shown an immune response in all of the healthy adults vaccinated, preliminary results reported in the New England Journal of Medicine have shown.1

The Zaire variant candidate vaccine rVSV-ZEBOV uses live recombinant vesicular stomatitis virus (rVSV), a livestock disease that generally causes no or only mild illness in humans, to carry DNA from Zaire ebolavirus with the aim of stimulating …

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