Insulin has never become a cheap generic drug in the US because of companies’ small changes to “evergreen” the patentBMJ 2015; 350 doi: https://doi.org/10.1136/bmj.h1535 (Published 20 March 2015) Cite this as: BMJ 2015;350:h1535
- Susan Mayor
Drug companies have made incremental improvements to insulin that have kept it as a patented medicine in the United States for more than 90 years, shows a study tracing the drug’s history.
“The history of insulin highlights the limits of generic competition as a public health framework,” said the study authors, Jeremy Greene and Kevin Riggs, of Johns Hopkins University School of Medicine in Baltimore, USA, writing in the New England Journal of Medicine. They warned, “Nearly a century after its discovery, there is still …
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