Pre-exposure prophylaxis protects against HIV infection in real world setting, study finds

BMJ 2015; 350 doi: (Published 25 February 2015) Cite this as: BMJ 2015;350:h1076
  1. Zosia Kmietowicz
  1. 1The BMJ

Pre-exposure prophylaxis (PrEP) with a daily antiretroviral drug is highly protective among men who have sex with men in England and reduced the risk of HIV infection by 86%, a study has found. NHS England is now considering whether PrEP should be used in the NHS to reduce the rate of new HIV infections, which stands at about 2500 a year and has remained unchanged for 10 years.

Michael Brady, medical director at the HIV charity the Terrence Higgins Trust, called the study results “a game changer” and urged the government “to make PrEP a key priority in the fight against HIV.”

The study has not yet been peer reviewed or published, but the results were presented at the Conference on Retroviruses and Opportunistic Infections in Seattle, Washington, on 24 February. It looked at whether offering PrEP in the form of …

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