Research News

Tamoxifen reduces breast cancer rate in at-risk healthy women by nearly a third, finds study

BMJ 2014; 349 doi: https://doi.org/10.1136/bmj.g7596 (Published 12 December 2014) Cite this as: BMJ 2014;349:g7596
  1. Zosia Kmietowicz
  1. 1The BMJ

Taking tamoxifen for five years has been found to reduce the rate of breast cancer by 29% among healthy women at high risk of developing the disease, a long term study has found.

Between 1992 and 2001 7154 women aged 35-70 with an increased risk of breast cancer, primarily because they had a family history, were enrolled into the International Breast Cancer Intervention Study I and were randomly allocated to receive either tamoxifen (3579) or placebo (3575) for five years. Researchers continued to track the health of all …

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