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Clinical trials of Ebola therapies to begin in December

BMJ 2014; 349 doi: https://doi.org/10.1136/bmj.g6827 (Published 14 November 2014) Cite this as: BMJ 2014;349:g6827
  1. Anne Gulland
  1. 1London

The first clinical trials of therapies for Ebola virus disease will begin next month in the treatment centres run by Médecins Sans Frontières in Guinea.

At a press conference in Geneva the principal investigators of the trials announced that three therapies would be tested at three separate sites. They said that the trials would begin in December, and 100-200 patients at each treatment centre would undergo testing.

A team led by the French National Institute of Health and Medical Research will test the antiviral drug favipiravir in Gueckedou, the antiviral brincidofovir will be tested by a consortium led by the University of Oxford at a site yet to be announced, and convalescent whole blood and plasma therapy will be tested by a group led by the Antwerp Institute of …

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