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Remote ischaemic preconditioning and other stories . . .

BMJ 2014; 349 doi: https://doi.org/10.1136/bmj.g6438 (Published 30 October 2014) Cite this as: BMJ 2014;349:g6438

It’s the squeeze that protects organs. Remote ischaemic preconditioning seems too good, and too simple, to be true. The latest evidence comes from a trial (Heart 2014, doi:10.1136/heartjnl-2014-306178) of patients undergoing elective coronary artery bypass graft surgery or valve surgery (or both). Patients were randomised to receive simultaneous upper arm and thigh cuff inflation and deflation (two cycles of five consecutive minutes of each) or control (cuffs not inflated). Those whose cuffs were inflated had half the rate of acute kidney injury and postoperative atrial fibrillation as controls, and their cardiac troponin levels were 26% lower overall.

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