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Scientists call for more multi-arm clinical trials to speed up approval of new drugs

BMJ 2014; 349 doi: https://doi.org/10.1136/bmj.g4812 (Published 25 July 2014) Cite this as: BMJ 2014;349:g4812
  1. Adrian O’Dowd
  1. 1London

Experts have called for more multi-arm clinical trials instead of the traditional two arm studies, to allow new drugs to reach patients more quickly and to save money.

Academics from the Medical Research Council’s clinical trials unit have recommended a change in approach to trials, in a commentary published online in the Lancet on 25 July.1 Traditionally, researchers carry out a two arm study—where one treatment is compared with another—rather than doing a multi-arm trial, where several …

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