NNT is highly misleading when assessing chronic disease preventionBMJ 2014; 349 doi: https://doi.org/10.1136/bmj.g4167 (Published 15 July 2014) Cite this as: BMJ 2014;349:g4167
- Timo E Strandberg, professor1
- 1Universities of Helsinki and Oulu, PO Box 22, FI-00014 Helsinki, Finland
The use of absolute risk reduction and number needed to treat (NNT) instead of relative risk reduction (RRR) has been advocated when communicating the effect of various treatments to patients.1 2 However, the use of NNT in the prevention of chronic disease may be highly misleading and may underestimate long term benefits.
In a hypothetical primary prevention trial …