Research News

HRT risks outweigh benefits for chronic disease prevention, research confirms

BMJ 2013; 347 doi: http://dx.doi.org/10.1136/bmj.f5885 (Published 02 October 2013) Cite this as: BMJ 2013;347:f5885
  1. Jacqui Wise
  1. 1London

Hormone replacement therapy (HRT) is not recommended for chronic disease prevention as the risks outweigh the benefits, further follow-up from the large Women’s Health Initiative trials has found.1

The studies included more than 27 000 postmenopausal women aged between 50 and 79 who were enrolled at 40 centres in the United States.

One trial was for women with an intact uterus who received either conjugated equine oestrogens (0.625 mg a day) plus medroxyprogesterone acetate (2.5 …

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