Letters Nicorandil induced perianal ulceration

Discontinue treatment with nicorandil associated with ulceration to avoid major reconstructive surgery

BMJ 2013; 347 doi: https://doi.org/10.1136/bmj.f4295 (Published 16 July 2013) Cite this as: BMJ 2013;347:f4295
  1. Andrew J Robinson, fixed term specialty training appointment year 3, plastic surgery1,
  2. J Howard Stevenson, consultant plastic surgeon2
  1. 1Northern Ireland Plastic and Maxillofacial Service, Ulster Hospital, Belfast BT16 1RH, UK
  2. 2Ninewells Hospital, Dundee DD1 9SY, UK
  1. arobinson13{at}doctors.org.uk

The association between perianal ulceration and nicorandil is now well established. We agree with Kulakov and colleagues that such ulcers usually heal spontaneously on discontinuation of the nicorandil, within a few months if nicorandil is the causative agent. …

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