Vitamin D deficiency

Position statements on vitamin D deficiency are no substitute for well designed studies

BMJ 2013; 346 doi: http://dx.doi.org/10.1136/bmj.f956 (Published 19 February 2013)
Cite this as: BMJ 2013;346:f956

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  1. Stephen S Nussey, professor of endocrinology1
  1. 1St George’s Hospital Medical School, London SW17 0RE, UK
  1. s.nussey{at}stgeorges.nhs.uk

The recent statement by the British Paediatric and Adolescent Bone Group causes concern in an era that demands objectivity.1 Where is the evidence for the statements made? Which criteria are the definition of vitamin D deficiency based on? None is stated.

Why is a cut-off point of 25 nmol/L (1 nmol/L=0.4 ng/mL) for serum 25-hydroxyvitamin D3 (25-(OH)D3) concentration used? No reason is given. This value is much lower than that used by other expert bodies, including paediatric societies.2 Autopsy data (albeit from …

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