Research News

Co prescription of statins and antibiotics linked to extra deaths

BMJ 2013; 346 doi: (Published 18 June 2013) Cite this as: BMJ 2013;346:f3963


Evidence is growing of an important drug interaction between widely used statins and antibiotics. Clarithromycin and erythromycin inhibit the cytochrome P450 isoenzyme that metabolises atorvastatin, simvastatin, and lovastatin. Co-prescription of any combination of these statins and antibiotics increases blood concentrations of the statin, …

Sign in

Free trial

Register for a free trial to to receive unlimited access to all content on for 14 days.
Sign up for a free trial