Letters Chlortalidone for hypertension

UK supply of chlortalidone for hypertension must be restored

BMJ 2013; 346 doi: http://dx.doi.org/10.1136/bmj.f3076 (Published 15 May 2013) Cite this as: BMJ 2013;346:f3076
  1. Emma E Morrison, specialist trainee year 3, clinical pharmacology1,
  2. Emma J Turtle, McKenzie lecturer in clinical pharmacology1,
  3. David J Webb, Christison professor of therapeutics and clinical pharmacology1
  1. 1Pharmacology, Toxicology and Therapeutics, BHF Centre for Research Excellence University of Edinburgh, Queen’s Medical Research Institute, Edinburgh EH16 4TJ, UK
  1. emma.morrison{at}nhs.net

In 2011 the National Institute for Health and Care Excellence (NICE) updated UK hypertension guidance.1 Bendroflumethiazide 2.5 mg, still the most commonly prescribed UK antihypertensive,2 was replaced by chlortalidone (12.5-50 mg) as the recommended thiazide-like diuretic, because of its much stronger evidence …

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