Letters Outpatient parenteral antimicrobial therapy

OPAT outcomes in endocarditis

BMJ 2013; 346 doi: https://doi.org/10.1136/bmj.f2484 (Published 24 April 2013) Cite this as: BMJ 2013;346:f2484
  1. Christopher J A Duncan, research fellow12,
  2. David A Barr, specialist registrar2,
  3. R Andrew Seaton, consultant in infectious diseases and general medicine2
  1. 1Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK
  2. 2Gartnavel General Hospital, Glasgow, Glasgow G12 0YN, UK
  1. chrisduncan{at}doctors.net.uk

As Chapman states,1 outpatient parenteral antibiotic therapy (OPAT) is increasingly seen as a viable management option for high risk patients with infective endocarditis. But in most studies treatment success is judged on clinical grounds (such as cure of infection). Because the benefits of this treatment derive from avoiding hospital admission while providing high standards of care to “low risk” patients, judgment on the …

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