Letters Dual blockade of the renin-angiotensin system

Authors’ reply to Messerli and colleagues

BMJ 2013; 346 doi: https://doi.org/10.1136/bmj.f2288 (Published 16 April 2013) Cite this as: BMJ 2013;346:f2288
  1. John H Laragh, professor of medicine, department of cardiothoracic surgery1,
  2. Jean E Sealey, research professor emerita of physiology and biophysics in medicine, department of medicine1
  1. 1Weill Cornell Medical College, New York, NY 10065-4896, USA
  1. jsealey{at}med.cornell.edu

Messerli and colleagues’ response to our suggestion that subsets of treated cardiovascular patients are sodium depleted with high plasma renin concentrations and cannot benefit from renin-angiotensin system blocking drugs is typical of the current “one size fits all” approach to the …

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